November 16th 1938: LSD (Lysergic acid diethylamide) is First Synthesized by Swiss Chemist Dr. Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland.
Five years passed, and LSD-25 sat on the shelf. Hofmann continued his work but he couldn’t shake the feeling that LSD-25 may have other properties that were missed in the initial testing. On a hunch, he re-synthesized it on April 16th, 1943. In the lab that day, he accidentally absorbed around 20 micrograms of LSD-25 in his skin and recorded in his journal that he had a remarkable experience, one he could only connect to the substance.